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A UK university has developed a non hygroscopic effervescent formulation with improved stability in the presence of small amounts of moisture and which addresses the challenges in effervescent product manufacturing, packaging and subsequent storage. The university is seeking industrial partners for technical cooperation or licensing of the technology to an industrial partner for product specific development.
The global market for effervescent products is estimated in the multi-billions of dollars and covers a wide range of industries including pharmaceutical, healthcare and household cleaning. However, the manufacture of effervescent formulations (powders/tablets) is not straight-forward as moisture in the atmosphere leads to the initiation of the neutralisation reaction between the key ingredients, degrading the product and rendering them less effective or unusable. The problem is exacerbated by the fact that organic acids are hygroscopic and readily absorb moisture from the atmosphere; this is enhanced when the acids are mixed with other excipients typical of most formulations. As a consequence manufacturing is performed at low humidity in specialist humidity controlled units. The controlled thermo-hygrometric conditions, high maintenance cost of processing equipment and special packaging materials make manufacturing of effervescent preparations expensive and challenging.
The key benefit of effervescent solid products is their ability to quickly dissolve in water, giving a convenient solid formulation that can quickly become a liquid formulation. This benefit is used over a range of industries, for example, over the counter medicines, food supplements, dental hygiene, household cleaners, detergents and agrochemicals.
A UK university has developed a non-hygroscopic effervescent formulation which provides an alternative to traditional effervescent products thus avoiding their drawbacks. The university is seeking industrial partners for technical cooperation or licensing of the technology to an industrial partner for product specific development.
The benefits of non-hygroscopic effervescent formulations:
• Allows processing without the necessity of a humidity controlled environment.
• Significantly reduces the energy costs associated with manufacturing.
• Avoids need for specialised equipment, standard granulating and tabletting equipment can be used.
• Reduces equipment costs and gives more flexibility to the manufacturing plant.
• Negates need for specialist storage requirements for final products
• Avoids need for specialised packaging materials
Type of partner sought - SME or large industrial partner
Specific area of activity of the partner - manufacture of over the counter medicines, food supplements, dental hygiene, household cleaners, detergents and agrochemicals
Task to be performed by the partner sought - Assess suitability of technology for application and consider partnership / licensing