These are the details for the profile Contract research organisation providing pre-clinical drug discovery and development services to companies, R&D organisations, universities .
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A UK contract research organisation (CRO) specialised in bio-analytical and ADME (absorption, distribution, metabolism & excretion) support for non-regulatory pre-clinical drug discovery, research and method development. The company is looking for companies, R&D organisations and universities, operating in the pharmaceutical, animal health and environmental sectors, who require outsourcing services and services agreement for integrated projects or stand alone activities.
The UK CRO provides bespoke R&D solutions to meet individual client requirements. The full range of services cover bio analytical support for pre clinical drug discovery and development testing in vitro, in vivo pharmacokinetics (PK) and ADME studies (Absorption, Distribution, Metabolism & Excretion).
Key services include:
• UV, HPLC (high pressure liquid chromatography), LC-MSMS (liquid chromatography mass spectrometry)
• Enzyme immunoassay and ELISA
• Bio-analysis of study samples
• Management of studies using a third party contractor
In vitro ADME:
• Analysis of cellular uptake during in vitro experiments
• Absorption studies using PAMPA (parallel artificial membrane permeability assay), CACO-2 (cell line), PGP (transporter protein) and other transporter enzyme assays
• Metabolism studies using cyp450 enzymes, microsomes, S9, cytosol or hepatocytes
• Distribution: protein binding (equilibrium dialysis), tissue binding
• Sample stability
• Impurity analysis
• Pesticide residue concentrations
The company is looking for outsourcing and service agreements with industrial, R & D and academic clients from the pharmaceutical, animal health and environmental sectors. The company is particularly interested to work with partners on small studies which require fast turnaround.
The UK company has been trading since 2008 and founders each have over 30 years of bioanalytical experience in pharmaceutical R&D, biotech, academia, manufacturing and CROs, particularly in the fields of drug discovery and DMPK . The company has worked with globally recognised universities, R & D organisations and industry.
The UK company provides customised R & D solutions and offers a variety of services covering pre-clinical drug discovery and development.
The company is easily accessible and capable of working to strict and fast turn around times and offers clients a highly professional, personal and discreet service.
The company applies a consistently high level of care to each and every project regardless of size.
The company provides competitive rates and applies an "all inclusive" price structure.
The company is looking for service and outsourcing agreements with companies, R & D organisations and universities operating in the pharmaceutical, animal health and environmental sectors. The company is particularly looking for those seeking support with small studies requiring a fast response.