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Personalized tissue engineering platform using adipose-derived mesenchymal stem cells for bone and soft tissue regeneration

Summary

Profile Type
  • Technology offer
POD Reference
TOHU20250717005
Term of Validity
17 July 2025 - 17 July 2026
Company's Country
  • Hungary
Type of partnership
  • Commercial agreement with technical assistance
  • Research and development cooperation agreement
Targeted Countries
  • All countries
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General information

Short Summary
A Hungarian university offers a technology for personalized therapeutic tissue production using adipose-derived mesenchymal stem cells. The platform supports 3D bioprinting of patient-specific bone and adipose tissues. Partners are sought for research cooperation or commercial agreement with technical assistance.
Full Description
A Hungarian research university has developed a cutting-edge platform for regenerative medicine. The technology uses mesenchymal stem cells (MSCs) isolated from human adipose tissue, allowing for personalized differentiation into bone or fat tissues.

The innovation includes a validated methodology for:
- isolation of MSCs from adipose tissue,
- patient-specific differentiation protocols, and
- preparation of personalized bone, cartilage, or fat-based tissue structures.

This system is fully compatible with 3D bioprinting technologies and allows the use of radiological imaging (MRI, CT) converted into CAD-based 3D models for implant design. As a result, patient-specific implants and tissue structures can be printed for medical and cosmetic use.

The solution offers significant advantages in autologous tissue generation, reducing immune responses and enabling faster recovery. It is applicable in orthopaedic, reconstructive, and cosmetic surgery.

The university seeks international partners for technical validation, research collaboration, or commercialization of the technology.
Advantages and Innovations
- Patient-specific therapeutic solutions using autologous stem cells.
- Reduced risk of rejection and improved healing outcomes.
- Integration of CAD with MRI/CT imaging for customized 3D tissue design.
- Innovative workflow from tissue sampling to final 3D-printed implant.
- Applicable in both medical and cosmetic applications (e.g., breast reconstruction).
Stage of Development
  • Available for demonstration
Sustainable Development Goals
  • Goal 3: Good Health and Well-being
IPR status
  • Secret know-how

Partner Sought

Expected Role of a Partner
The university is seeking:

- Research partners for clinical validation and further development.
- Medical technology companies for adaptation and integration into surgical workflows.
- Cosmetic or reconstructive clinics for piloting the technology.

The partner should have experience in regenerative medicine, 3D bioprinting, or implant design.
Type and Size of Partner
  • Big company
  • University
  • SME 11-49
  • SME 50 - 249
  • R&D Institution
Type of partnership
  • Commercial agreement with technical assistance
  • Research and development cooperation agreement

Dissemination

Technology keywords
  • 06003001 - Bioinformatics
  • 01003012 - Imaging, Image Processing, Pattern Recognition
  • 06002002 - Cellular and Molecular Biology
  • 06001019 - Stem cell Technologies
Market keywords
  • 05003001 - Therapeutic services
  • 05007006 - Computer-aided diagnosis and therapy
  • 05003003 - Surgical implants
Targeted countries
  • All countries

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