Enterprise Europe Network

Cost-effective encapsulation of active agents or drugs to be released against pollution, corrosion, or medical condition.

Country of origin:
Country: 
FRANCE
Opportunity:
External Id: 
TOFR20181121001
Published
22/11/2018
Last update
23/11/2018
Expiration date
24/11/2019

Keywords

Partner keyword: 
Extraction
Adsorption
Other Processes
Micro- and Nanotechnology
Drug delivery and other equipment
Plant health
Chemical and solid material recycling
Other pollution and recycling related
Other research and experimental development on natural sciences and engineering
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Summary

Summary: 
An innovative process for the synthesis of Layered Double Hydroxide (LDH) is ready to be transfered. Its simple and energy-saving protocol can customize LDH which includes active agents to be released for pollutant extraction, corrosion inhibition, or drug delivery. A French Technology Transfer Office (TTO) is looking for a licensing agreement or a technical cooperation agreement with companies dealing with polluted site clean-up products, anti-corrosion coatings, or drugs encapsulation.

Description

Description: 

A new process for the synthesis of Layered Double Hydroxide (LDH) has been designed as a cost-saving and efficient encapsulation of active agents. Moreover, it allows to customize materials or chemical preparations to be released against pollution, corrosion, or medical condition.
It has been set up and patented by a French research team which is represented by a Technology Transfer Office (TTO) for its industrial partnership and industrial property management.

Market challenges :
LDHs have a broad range of applications in catalysis, electrochemistry, biomedical and environmental sciences. In particular, LDHs can be used for anion exchange and anion extraction processes and as a controlled release drug or phytochemicals delivery systems.
Current LDH synthesis method requires a complex protocol and high energetic cost. In addition, they have a limited range of applications.

State of the art :
LDHs are widely used as acidity regulators. Moreover, they have got interesting properties such as a large specific surface area, which is very useful for heterogenous catalysis. As an example, it has been tested for biodiesel synthesis. Until now, the only LDH available on the market is Mg-Al carbonate hydrotalcite.
There are other promising use cases for LDHs such as pollutant capture or drug delivery. Nevertheless, there is no simple, efficient and cheap method to prepare customized LDHs dedicated to those applications. Especially, there is a strong need for a cost-effective method of anion extraction from a medium (e.g. to depollute or recycle a substance).

Proposed technology :
The patented technology consists in a new process for exchanging interlayer anions of LDH with other anions whose affinity for the LDH is lower than the one of the initial interlayer anions.
This method allows the preparation of customized LDH for extracting anions from a liquid medium (with a following step to regenerate the LDH).
As compared to the synthesis of Mg-Al carbonate hydrotalcite which is the only one available on the market, the patented process is efficient and cost-effective for the extraction of any metal or any pollutant in liquid medium. It can also be applied to drug controlled release for human or vegetal health treatment.

Requested partner :
Manufacturers or end-user companies dealing with pollutant capture, corrosion inhibition, or even drug delivery are requested for either a licensing agreement, or a technical cooperation agreement on a specific usecase.

Keywords :
Layered Double Hydroxide, aqueous solution metal extraction, recycling, depollution, encapsulation, drug vectorisation.

Advantages & innovations

Cooperation plus value: 
The innovative encapsulation process can be implemented in a continuous way, and can use as a starting point any LDH, including the commercially available Mg-Al carbonate hydrotalcite. The proposed technology allows an easy access to LDHs with various types of interlayer anions e.g. drug, biomolecule, catalyst, anti-corrosive agent, depending on the application considered : - Environment : depollution, recycling, extraction in liquid medium of critical and strategic metals from electronic waste, - Paint industries : encapsulation of anionic active substance in paints as corrosion inhibitor, - Pharmaceutical industries : encapsulation of drugs e.g. ibuprofen, - Phytosanitary industries : encapsulation of herbicids e.g. picloram.

Stage of development

Cooperation stage dev stage: 
Available for demonstration

Partner sought

Cooperation area: 
The requested partner may be a company interested in the controlled release of active agents to be used for pollutant capture, corrosion inhibition, or even sustained drug release. Expected outcomes are either : - a licensing agreement prior to an industrial development of an innovative product based on the proposed technology, or - a technical cooperation agreement in order to set up a customized LDH for a specific use case in any of the following application fields : pollution, corrosion, drug vectorisation for health or plant cultivation.

Type and size

Cooperation task: 
SME 11-50,SME <10,>500 MNE,251-500,SME 51-250,>500