Enterprise Europe Network

A French company developing technology for potentiation of therapeutic antibodies seeks partners from immunotherapy market who want to increase therapeutic performances of their antibodies

Country of origin:
Country: 
FRANCE
Opportunity:
External Id: 
TOFR20210308002
Published
12/03/2021
Last update
19/03/2021
Expiration date
20/03/2022

Keywords

Partner keyword: 
Pharmaceutical Products / Drugs
Protein Engineering
Molecular design
Oncology
Pharmaceuticals/fine chemicals
Research and experimental development on biotechnology
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Summary

Summary: 
A French biotech company has a proprietary technology allowing the potentiation of exogenous therapeutic proteins (enzymes or antibodies). The goal is to develop new engineered antibodies together with European companies allowing a higher capacity to degrade pathogenic antigens. This technology concerns many immunotherapies in inflammatory and immune diseases, cancers or rare diseases.The company would like to achieve technical cooperation, research or license agreement.

Description

Description: 

A French biotech company located in Montpellier has patented vectors allowing a smooth engineering of therapeutic antibodies thus leading to an improvement of their biological properties. The technology improves the degradation of the antigen and increases the efficacy of the antibody. The higher efficacy can allow the decreasing of side effects for the patient and reduce the doses of the therapeutic treatment. Moreover, this new class of engineered antibodies can be patented for therapeutic use.

The company has a deep knowledge in:
- Synthesis of glycovectors and protein engineering,
- Preclinical proof-of-concept in cell cultures and murine models,
- Patent delivery and medical drug designation.

Capacity of production :
- vectors > 10 kg under Good Manufacturing Practices (GMP) standards

Thanks to its home skills and equipment and to the surrounding scientific platforms, the company benefits of all the facilities to perform biological, biochemical, analytical and chemical experiments. The company searches a partner who already produces a therapeutic antibody whose mechanism of action concerns the degradation of the antigen. The grafting of the vectors on antibodies will increase their therapeutic efficacy and will generate Intellectual Property.

This concept could be applied to immunotherapies in the area of oncology, inflammatory or auto-immune diseases or rare diseases. The company wishes to establish suitable and long-term business partnerships through technical cooperation agreement, research or license agreement.

Advantages & innovations

Cooperation plus value: 
The targeting technology is a breakthrough innovation for immunotherapies leading to a better degradation of antigens. This technology has large applications in the immunotherapies of inflammatory and immune diseases, cancers and rare diseases. The company has exclusive worldwide licenses to develop this technology with different European companies involved in these therapeutic fields.

Stage of development

Cooperation stage dev stage: 
Project in negotiations - urgent

Partner sought

Cooperation area: 
The company looks for partners already introduced in the immunotherapy market who seek to develop new antibodies under GMP standards or antibodies existing in the clinic and want to increase their therapeutic performances. The partner will propose an antibody for engineering with the proprietary vectors for a better efficacy and a higher antigen degradation. The characterization and the preclinical development of the engineered antibody will be performed by the two partners. Different types of partnerships can be considered such as EU grant application (meaning that partners could go for a European collaborative project), technical cooperation, research or license agreements.

Type and size

Cooperation task: 
>500 MNE,251-500,SME 51-250,>500