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Grapevine genome of cultivars sequencing system for wine production concerning quality and safety

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Partner keyword: 
Gene Expression, Proteome Research
Crop Production
Plant health
Wine and liquors


Italian bio-informatics SME offers a system for RiboNucleicAcid RNA-seq analysis of different grapevine genome cultivars. It's a knowledge base implementing a set of bioinformatics tools for the analysis of grapevine genomes, focused to improve knowledge of its varieties on adaptability to different climatic conditions, phenological phases, diseases, geographic locations. Wine producers, agriculture farm, agro-industry firm partners are sought for technical cooperation and/or license agreement.



Grapevine (Vitis vinifera) is the most important fruit species in the modern world. Wine and table grapes sales contribute significantly to the economy of major wine producing countries. The most relevant goals in wine production concern quality and safety. In order to significantly improve the achievement of these objectives and to gain biological knowledge about cultivars, a genomic approach is the most reliable strategy. The recent
grapevine genome sequencing offers the opportunity to study the potential roles of genes and microRNAs (RiboNucleicAcid) in fruit maturation and other physiological and pathological processes. Although several systems allowing the analysis of plant genomes have been reported, none of them has been designed specifically for the functional analysis of grapevine genomes of cultivars under environmental stress in connection with microRNA data.
The technology offered by an Italian bio-informatics SME is designed for the functional analysis of grapevine genomes of cultivars present in Italy (Sicily). The system allows the analysis of RNA-seq experiments of two different cultivars, namely Nero d’ Avola and Nerello Mascalese. Samples were taken under different climatic conditions of phenological phases, diseases, and geographic locations. The system web interface is equipped with data analysis modules for grapevine genomes. In particular users may analyze the current genome assembly together with the RNA-seq data through a customized version of GBrowse (Genome Brows).
In addition the new techniques provided by modern genetics enable real-time monitoring of the health status of crops, leading to a preventive assessment of plant health, and the impact that pathologies may have on production, and therefore on the Human health.
The company is looking for license agreement to utilize the bioinformatics tools and/or technical cooperation agreement for further possible development of this technology.
Typical partners could be grapes and/or wine producers, agriculture farm, agro-industry firm.

Advantages & innovations

Cooperation plus value: 
The main advantages are for the human health which will be indirectly obtained from the development of software tools that will enable the cultivation of products that contain large amounts of beneficial substances, such as antioxidants, with a lesser need for plant protection. This will be accompanied by additional software tools to assess the impact on human health of plant protection products, and the selection of those products that have a lesser negative impact on the most common human pathologies in areas where agricultural products are sold. The need to produce crops, and organic products, promoting a better lifestyle has emerged in recent years. Various agricultural products have shown important properties in the prevention of pathologies through the presence of substances, such as antioxidants, that have a protective effect on human health. In addition other advantages are connected to the realization of smart cultivations whose use promotes a better lifestyle. This will be achieved by: --characterizing those plants that reduce the need of plant protection products; -- timely identifying diseased plants; --identifying Phytopharmaceuticals which do not affect organoleptic properties of cultivar which therefore have positive effect on human health features such as: aging, compatibility with heart, respiratory or metabolic diseases. The innovations are connected mainly with the use of computer predictive and simulation tools to speed up the identification and the development of new plant protection products, with respect to the past, enabling a priori assessment of the impact on human health.

Stage of development

Cooperation stage dev stage: 
Available for demonstration

Partner sought

Cooperation area: 
- Type of partner sought: companies - SMEs and large companies, as well. - Specific area of activity of the partner: especially the wine producers, partners from the wine industry, agriculture farm, agro-industry firm. -Type of agreements: license agreement to utilize the bioinformatics tools and/or technical cooperation agreement for further possible development of this technology

Type and size

Cooperation task: 
SME <10