Enterprise Europe Network

A Korean SME offers its technology of PNA (Peptide Nucleic Acid)-based molecular diagnostic for market-leading performance

Country of origin:
Country: 
SOUTH KOREA
Opportunity:
External Id: 
TOKR20200730001
Published
30/07/2020
Last update
17/08/2020
Expiration date
18/08/2021

Keywords

Partner keyword: 
Diagnostics, Diagnosis
Medical Technology / Biomedical Engineering
In vitro Testing, Trials
In vitro Testing, Trials
In-vitro diagnostics
Molecular diagnosis
Diagnostic equipment
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Summary

Summary: 
A Korean company expertise in manufacturing PNA (Peptide Nucleic Acid)-based genetic detection-related products and possess its original technology. The company is currently seeking partners interested in cooperation under the commercial agreement with technical assistance, license agreement, or technical cooperation. The company produces various molecular diagnostic products for oncology and detection of infectious diseases and have been supplying products as clinical use for many years.

Description

Description: 

A Korean company that has a competitive edge in the field of gene/molecular diagnostics is currently seeking partners to further expand its market in Europe. The Korean company has been aiming to become a global leader in the field of molecular diagnostics based on its Peptide Nucleic Acid (PNA) technology (which is also known as artificial genetic material) that has been drawn a huge attention among researchers as a promising material especially, for diagnostic and therapeutic use in early stage of its development.

PNA has been firstly invented by Copenhagen Inventor Group (CIG), and based on the self-developed mass production technology, this Korean company has secured the exclusive rights for its worldwide supply. Currently, the Korean company has retained the largest number of intellectual property rights on PNA and its applied technology. Based on that, the company has secured its own various source technologies that enable a multiplex target diagnosis and detecting low level of mutation or Single Nucleotide Polymorphism, SNP.

*Below is the main feature of each technology:

First representative technology (hereinafter name it “A”) is the PNA-based PCR (Polymerase Chain Reaction) Clamping that selectively amplifies only the mutated target DNA sequence while suppressing the wild type DNA sequences during the process. The technology takes full advantages of PNA probes that have strong binding affinity and specificity to its complementary strands and property of not being used at all by DNA (DeoxyriboNucleic Acid) polymerase as primer.

Another technology hereinafter named it “B” is Multiplex Melting Curve Analysis using fluorescence labeled PNA probe. Not only it allows to detect small amount of mutation with high sensitivity, but it also made it possible to find genotype multiple mutations simultaneously. This technology uses the phenomena that each probe has its own melting temperature (Tm) value for the sequence changes of the target gene.

Lastly, there’s a novel technology that integrates A and B technologies, hereinafter name it “C”. The small portion of mutant type DNA can be detected with the highest sensitivity and it makes it possible to process various genotypes of DNA simultaneously.

Following the open innovation era, the company is seeking opportunities for collaboration with various organizations worldwide, while providing its accurate genetic diagnosis technology to lead the biomaterials and genetic diagnosis market. Considering partnership types could be commercial agreement with technical assistance, license agreement or technical cooperation agreement, but any other types of partnership is open to be considered through discussions.

Advantages & innovations

Cooperation plus value: 
- Has real world clinical data for years (Clinically proven products) - Own production for raw material for diagnostics technology - Real-Time PCR based kit - Extremely high sensitivity and specificity for liquid biopsy (0.1% Limit of Detection) - Multiplex availability using various fluorescence dyes - Developed diagnostics kits as a platform to run with same PCR conditions - Open system allowing the use of various PCRs in the market - Products are used in the clinical field for years. (Clinically proven products) - Key materials are manufactured and handled internally for quality control

Stage of development

Cooperation stage dev stage: 
Already on the market

Partner sought

Cooperation area: 
The potential partner type would be company in Europe, especially in the field of healthcare. The Korean company is looking for a cooperation with international partners, while providing its innovative genetic diagnosis technology under the commercial agreement with technical assistance, license agreement, or technical cooperation agreement particularly.