Summary
- Profile Type
- Technology offer
- POD Reference
- TOSK20240412009
- Term of Validity
- 16 April 2024 - 16 April 2025
- Company's Country
- Slovakia
- Type of partnership
- Commercial agreement with technical assistanceInvestment agreement
- Targeted Countries
- All countries
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General information
- Short Summary
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An innovative honey preparation for the local treatment of long-term non-healing wounds has been developed by a team of inventors from an established Slovak scientific and research institute and a Slovak university.
The novelty of the honey preparation consists in the use of a combination of ascorbic acid with honey to increase.
The preferred cooperation type is commercial agreement or investment agreement. - Full Description
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Nowadays, the term “medical honey” is becoming increasingly known to the professional and general public. Products or medical aids, which are based on such honey, are emerging on the world market. It is certified honey that can be used for therapeutic purposes, especially for the treatment of burn injuries and acute and chronic wounds. In addition to quality parameters, medicinal honeys have significant biological properties. Emphasis is placed especially on their antibacterial properties. Honey as a natural product is a source of trace elements, vitamins, amino acids and so on. A natural component of honey is also ascorbic acid (vitamin C).
Although honey has certain antibiofilm properties, its effect is limited and dilution of honey may on the contrary induce stimulation of biofilm formation in the wound. For this reason, it is necessary to enrich honey with naturally occurring substances in honey, which have a biological effect without negative side effects, and to increase its effect against planktonic as well as biofilm-bound bacteria, in particular Gram-negative bacteria. Honey intended for direct clinical application must be sterilized, most often by means of ionizing radiation, which does not have a negative effect on the antibacterial or antibiofilm activity of honey. However, ionizing radiation can cause destruction or subsequent aggregation of proteins/peptides in honey. Destruction of proteins/peptides in honey can be prevented by the addition of specific protective substances, thus preserving its antibacterial capacity.
A team of inventors from a Slovak scientific and research institute and a Slovak university has managed to substantially eliminate the above-mentioned shortcomings by adding (in appropriate amounts) ascorbic acid to honey, which is usually used as an antioxidant or a means of lowering the pH. The addition of ascorbic acid to honey intended for medical use has increased its antibacterial and antibiofilm activity. In addition, ascorbic acid stabilizes biologically active substances of the peptides/proteins type against undesired degradation or aggregation during the sterilization process by ionizing radiation.
The institution is looking for a partner to cooperate with via commercial agreement or investment agreement. - Advantages and Innovations
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• increase of antibacterial and antibiofilm activity of honeys (2- to 5-fold against Gram-negative bacteria), which are planned or are already being used in clinical practice, while it may be honeys of different botanical and geographical origin,
• stabilization of antibacterial components of honey (bee antibacterial/antibiofilm peptide) even during the process of honey sterilization by means of ionizing radiation. - Stage of Development
- Lab tested
- Sustainable Development Goals
- Goal 17: Partnerships to achieve the GoalGoal 9: Industry, Innovation and Infrastructure
Partner Sought
- Expected Role of a Partner
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The use of the preparation is expected primarily in wound healing management and ophthalmology, but also wherever it is necessary to locally eliminate bacterial infection.
The institute and the Slovak university are looking for a partner to cooperate with via commercial agreement (an industrial partner for licensing of this technology is sought) or investment agreement (a partner to sell this technology to is sought). - Type and Size of Partner
- Big companySME 50 - 249
- Type of partnership
- Commercial agreement with technical assistanceInvestment agreement
Call details
- Coordinator required
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Yes
Dissemination
- Technology keywords
- 06001013 - Medical Technology / Biomedical Engineering
- Market keywords
- 05007007 - Other medical/health related (not elsewhere classified)07004002 - Health and beauty aids
- Targeted countries
- All countries