Summary
- Profile Type
- Technology offer
- POD Reference
- TOES20240408003
- Term of Validity
- 8 April 2024 - 8 April 2025
- Company's Country
- Spain
- Type of partnership
- Commercial agreement with technical assistanceInvestment agreementResearch and development cooperation agreement
- Targeted Countries
- All countries
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General information
- Short Summary
- A Spanish University and a Spanish Hospital have developed a specific device for the evaluation and monitoring of the survival of grafted skin (flaps) in patients. Using optical technology (Diffuse Reflectance Spectroscopy, DRS) the perfusion status of the tissue is quantitatively determined in a non-invasive way and independent on parameters such as oxygen saturation, as opposed to the INVOS systems. It is useful in skin transplants such as plastic surgery, major burns or dermatology.
- Full Description
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Free flaps are complex surgical tools that are the final reconstructive step for many defects after cancer or trauma. Vascular failure is the most frequent and serious complication and can lead to total loss of the flap. The diagnosis of this failure is sometimes complex or made too late, making it impossible to save the flap. Accurate real-time knowledge of the perfusion status of free flaps, both during surgery and in the postoperative period, is vitally important to ensure flap viability.
A Spanish University and a Spanish Hospital have developed a medical device to monitor the perfusion status of skin flaps, which allows to determined quantitatively the perfusion state of a tissue independently of oxygen saturation and in a harmless way. The device is based on DRS, Diffuse Reflectance Spectroscopy. When this light is incident on tissue, analytes such as hemoglobin present specific spectral responses in their interaction with light. This allows the estimation of their concentration in the tissue and monitor the state of blood perfusion of the tissue.
The design of the system is based on different LED emitters, with very specific wavelengths, whose beams are combined and used to illuminate the tissue area to be analyzed. Analysis of the intensity of light emerging from the graft allows quantification of the state of perfusion status in the skin flap. It is necessary to highlight that the measurement principle allows the analysis to be carried out remotely and without the need for contact, so at a distance of a few centimeters from the flap it is perfectly feasible to carry out an accurate characterization.
In brief, for the first time, this tool makes available to clinical staff to have a system specifically designed for the analysis of flaps capable of providing an absolute or relative measure of the perfusion status of the flaps, their viability and potential problems. - Advantages and Innovations
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- Device developed and adapted specifically to evaluate the survival of grafted skin (flaps) in patients.
- Combined use of LED emitters at specific wavelengths optimized for correct operation.
- Adapted to general clinical use and operating rooms.
- It is not based on the level of oxygen saturation and is used without contact with the patient. Unlike INVOS systems, which use non-sterile stickers, connected by cables and only give acceptable results when oxygen saturation is close to 100%.
- Other systems use pharmacological compounds such as green indocyanine or Doppler laser, which differ quite a bit from the proposed solution.
- System developed specifically for the purpose, not like the current devices used that come from other purposes and, therefore, are not adapted or accurate.
- Non-invasive and non-contact, it is used about 4 cm from the patient.
- Greater speed, precision and effectiveness in the evaluation. - Stage of Development
- Available for demonstration
- Sustainable Development Goals
- Goal 17: Partnerships to achieve the GoalGoal 9: Industry, Innovation and InfrastructureGoal 3: Good Health and Well-being
Partner Sought
- Expected Role of a Partner
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They look for the following kinds of partner: Medical device companies, hospitals, health research centers, technology centers
They look for the following parter role: interested in developing, industrializing and/or selling the device. - Type and Size of Partner
- SME 11-49Big companySME <=10SME 50 - 249R&D Institution
- Type of partnership
- Commercial agreement with technical assistanceInvestment agreementResearch and development cooperation agreement
Call details
- Coordinator required
-
Yes
Dissemination
- Technology keywords
- 05003002 - Optics09001007 - Optical Technology related to measurements06001013 - Medical Technology / Biomedical Engineering06001017 - Surgery
- Market keywords
- 05004006 - Surgical instrumentation and equipment05005019 - 'Surgery and Anaesthesiology05003001 - Therapeutic services05005022 - Other clinical medicine
- Sector Groups Involved
- DigitalElectronicsHealth
- Targeted countries
- All countries
